Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10561156 | 0.80 | PTK2 (0.43) | PTK2KCNK3KCNK9PTPN1PTPN6 | |
| SCHEMBL302525 | 0.78 | — | — | |
| SCHEMBL826948 | 0.78 | — | — | |
| SCHEMBL3705840 | 0.78 | — | — | |
| SCHEMBL12043731 | 0.77 | TRPA1 (0.50) | PTK2KCNK3KCNK9PTPN1PTPN6 | |
| SCHEMBL753077 | 0.77 | PTK2 (0.47) | PTK2KCNK3KCNK9PTPN1PTPN6 | |
| Hydrochloric Acid SCHEMBL30164242 | 0.76 | KCNK3 (0.47) | PTK2KCNK3KCNK9PTPN1PTPN6 | |
| Hydrochloric Acid SCHEMBL10506306 | 0.76 | KCNK3 (0.47) | PTK2KCNK3KCNK9PTPN1PTPN6 | |
| Hydrochloric Acid SCHEMBL27597682 | 0.76 | PTPN1 (0.50) | PTK2PTPN1PTPN6PTPN11KMT2A | |
| SCHEMBL7046046 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715495-B1 | ANTIBACTERIAL AND ANTIFOULING OXATHIAZINES AND THEIR OXIDES | JANSSEN PHARMACEUTICA NV (BE) | 1998-03-11 | — | — | EP | disclosed |