SCHEMBL753077

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7505529	0.83	PTK2 (0.45)	PTK2ITGAVTRPA1ALDH1A1KDM4E
	SCHEMBL8791567	0.81	KDM4E (0.63)	PTK2ITGAVTRPA1ALDH1A1KDM4E
	SCHEMBL3273821	0.80	PTK2 (0.50)	PTK2ITGAVTRPA1KCNK3KCNK9
	SCHEMBL13383872	0.79	ALDH1A1 (0.62)	ALDH1A1CYP3A4MAPTHPGDRAB9A
	SCHEMBL3705840	0.77	—	—
	SCHEMBL13113148	0.77	PTK2 (0.44)	PTK2ITGAVTRPA1KDM4EMEN1
	SCHEMBL6360179	0.77	L3MBTL1 (0.50)	PTK2ITGAVTRPA1ALDH1A1KDM4E
	SCHEMBL8544772	0.77	PTK2 (0.47)	PTK2ITGAVTRPA1ALDH1A1KDM4E
	SCHEMBL11441592	0.76	GAA (0.57)	PTK2ITGAVTRPA1KDM4EKMT2A
	Acetic Acid SCHEMBL7505524	0.76	KCNK3 (0.45)	PTK2ITGAVTRPA1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.