Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544823 | 1.00 | KDM4E (0.54) | KDM4EMAPK1HCAR2ALDH1A1HPGD | |
| SCHEMBL11253548 | 0.83 | KDM4E (0.75) | KDM4EMAPK1ALDH1A1HPGDMAPT | |
| SCHEMBL11253542 | 0.83 | KDM4E (0.75) | KDM4EMAPK1ALDH1A1HPGDMAPT | |
| SCHEMBL28357180 | 0.82 | ABCG2 (0.65) | KDM4EMAPK1HCAR2ALDH1A1HPGD | |
| SCHEMBL9329482 | 0.82 | HCAR2 (0.66) | KDM4EMAPK1HCAR2ALDH1A1MAPT | |
| SCHEMBL9329490 | 0.82 | HCAR2 (0.66) | KDM4EMAPK1HCAR2ALDH1A1MAPT | |
| SCHEMBL9785216 | 0.81 | KDM4E (0.72) | KDM4EMAPK1ALDH1A1HPGDMAPT | |
| SCHEMBL5598744 | 0.81 | HCAR2 (0.74) | KDM4EHCAR2ALDH1A1HPGDMAPT | |
| SCHEMBL5598741 | 0.81 | HCAR2 (0.74) | KDM4EHCAR2ALDH1A1HPGDMAPT | |
| SCHEMBL8547188 | 0.80 | KDM4E (0.71) | KDM4EMAPK1HCAR2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691579-B1 | Electrophotographic elements and soluble cyclic sulfone electron transport agents | EASTMAN KODAK CO (US) | 1998-11-04 | — | — | EP | disclosed |
| US-5618950-A | Electrophotographic elements and soluble cyclic sulfone electron transport agents | EASTMAN KODAK COMPANY (US) | 1997-04-08 | — | — | US | disclosed |
| US-5500317-A | DICYANO-SULFONE COMPOUND | EASTMAN KODAK COMPANY (US) | 1996-03-19 | — | — | US | disclosed |
| EP-0691579-A1 | Electrophotographic elements and soluble cyclic sulfone electron transport agents | EASTMAN KODAK COMPANY (US) | 1996-01-10 | — | — | EP | disclosed |