Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 4/20 | 0.66 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | F3 | P13726 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.66 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329490 | 1.00 | HCAR2 (0.66) | HCAR2SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL5598741 | 0.89 | HCAR2 (0.74) | HCAR2SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL5598744 | 0.89 | HCAR2 (0.74) | HCAR2SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL28357180 | 0.87 | ABCG2 (0.65) | HCAR2SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL8544825 | 0.82 | KDM4E (0.54) | HCAR2SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL8544823 | 0.82 | KDM4E (0.54) | HCAR2SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL22146 | 0.81 | MAPT (1.00) | HCAR2SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL20518814 | 0.81 | MAPT (1.00) | HCAR2SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL20856054 | 0.81 | MAPT (1.00) | HCAR2SMN1; SMN2MAPTALDH1A1LMNA | |
| SCHEMBL20846 | 0.81 | MAPT (1.00) | HCAR2SMN1; SMN2MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5352802-A | Derivatives of 4H-thiopyran-1,1-dioxide | EASTMAN KODAK COMPANY (US) | 1994-10-04 | — | — | US | disclosed |
| US-5300385-A | Low voltage, high speed | EASTMAN KODAK COMPANY (US) | 1994-04-05 | — | — | US | disclosed |