Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4546868 | 0.76 | ADORA2A (0.53) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL1221520 | 0.75 | MAPT (0.54) | LTB4RMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL27430949 | 0.74 | ADORA2A (0.52) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL12590483 | 0.74 | SMN1; SMN2 (0.54) | LTB4RMEN1KMT2AALDH1A1KDM4E | |
| Biphenyl SCHEMBL28987640 | 0.73 | POLB (0.46) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL1997225 | 0.73 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL8224583 | 0.73 | KDM4E (0.41) | LTB4RKMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL4753824 | 0.71 | KMT2A (0.50) | MEN1KMT2AKDM4ESMN1; SMN2GAA | |
| SCHEMBL9545039 | 0.70 | NPC1 (0.53) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL28477802 | 0.69 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525825-B1 | Substituted dicarboxy pyridine compounds | EG & G WALLAC OY (FI) | 1998-12-09 | — | — | EP | disclosed |
| EP-0195413-B1 | Substituted pyridine derivatives | BAXTER DIAGNOSTICS INC (US) | 1993-11-18 | — | — | EP | disclosed |
| US-4925804-A | REPORTER MECHANISM FOR BIOSPECIFIC REACTIONS | BAXTER INTERNATIONAL INC. (US) | 1990-05-15 | — | — | US | disclosed |
| US-4761481-A | FLUORESCENT CHELATES, AMINE ACID COMPOUNDS | BAXTER TRAVENOL LABORATORIES, INC. (US) | 1988-08-02 | — | — | US | disclosed |