Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6912832 | 0.80 | ALDH1A1 (0.52) | KDM4EMAPTSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL8544878 | 0.73 | LTB4R (0.45) | KDM4EMAPTLTB4RSMN1; SMN2ALDH1A1 | |
| Benzidine SCHEMBL27854087 | 0.70 | TDP1 (0.55) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| Benzidine SCHEMBL27854089 | 0.70 | TDP1 (0.55) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| SCHEMBL9185380 | 0.70 | ADORA2B (0.39) | KDM4EMAPTSMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL5009552 | 0.70 | FFAR1 (0.46) | KDM4ESMN1; SMN2ALDH1A1CYP3A4KMT2A | |
| SCHEMBL8119878 | 0.70 | RXRA (0.66) | KDM4EMAPTSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL21880900 | 0.70 | ADORA2A (0.41) | KDM4ESMN1; SMN2ALDH1A1KMT2ANPC1 | |
| Benzidine SCHEMBL28841695 | 0.68 | CYP3A4 (0.52) | KDM4EMAPTHIF1ASLC22A6SLC22A8 | |
| Benzidine SCHEMBL28008037 | 0.68 | CYP3A4 (0.52) | KDM4EMAPTHIF1ASLC22A6SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127529-A | FORMS STABLE CHELATE COMPOUND USEFUL FOR LABELING BIOLOGICAL TARGETING COMPOUND RESIDUE | WALLAC OY (FI) | 2000-10-03 | — | — | US | disclosed |