Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.30 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.30 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.30 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.30 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544918 | 0.90 | POLB (0.31) | POLB | |
| SCHEMBL8538459 | 0.88 | AKR1C3 (0.33) | AKR1C3AKR1C2AKR1B10AKR1C4AKR1C1 | |
| SCHEMBL8539826 | 0.87 | EGLN1 (0.30) | EGLN1 | |
| SCHEMBL8545026 | 0.87 | EGLN1 (0.38) | CA12CA1CA2CA9SLC9A1 | |
| SCHEMBL8540996 | 0.82 | DDR1 (0.39) | EGLN1 | |
| SCHEMBL6938087 | 0.82 | SLC9A1 (0.54) | SLC9A1 | |
| SCHEMBL8538210 | 0.81 | SLC9A1 (0.44) | CA12CA1CA2CA9SLC9A1 | |
| SCHEMBL8541951 | 0.79 | SLC9A1 (0.41) | SLC9A1EGLN1 | |
| SCHEMBL8538519 | 0.79 | EGLN1 (0.40) | EGLN1 | |
| SCHEMBL8536966 | 0.78 | CNR2 (0.32) | CA12CA1CA2CA9SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |