Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 17/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8538519 | 0.90 | EGLN1 (0.40) | DDR1CCR2EGLN1 | |
| SCHEMBL8539475 | 0.88 | THRB (0.35) | DDR1CCR2EGLN1 | |
| SCHEMBL8538460 | 0.87 | THRB (0.39) | CCR2EGLN1 | |
| SCHEMBL8537164 | 0.86 | THRB (0.41) | — | |
| SCHEMBL8541620 | 0.85 | DDR1 (0.39) | DDR1CCR2EGLN1 | |
| SCHEMBL8541951 | 0.85 | SLC9A1 (0.41) | EGLN1 | |
| SCHEMBL8536966 | 0.84 | CNR2 (0.32) | — | |
| SCHEMBL8538459 | 0.83 | AKR1C3 (0.33) | DDR1 | |
| SCHEMBL8544927 | 0.82 | CA12 (0.30) | EGLN1 | |
| SCHEMBL8545026 | 0.81 | EGLN1 (0.38) | EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |