Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HBB | P68871 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 5/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15625970 | 0.81 | MAPT (0.56) | KDM1AMAPTKDM4EALDH1A1MAPK1 | |
| SCHEMBL19762195 | 0.77 | KDM4E (0.54) | KDM1AMAPTKDM4EALDH1A1MAPK1 | |
| SCHEMBL15305703 | 0.77 | KDM4E (0.61) | MAPTKDM4EALDH1A1MAPK1HPGD | |
| SCHEMBL15964261 | 0.75 | KDM4E (0.56) | MAPTKDM4EALDH1A1MAPK1HPGD | |
| SCHEMBL14154595 | 0.75 | MAPT (0.56) | KDM1AMAPTKDM4EALDH1A1MAPK1 | |
| SCHEMBL8541232 | 0.74 | PSEN1 (0.52) | HTTPOLB | |
| SCHEMBL27275931 | 0.73 | CYP19A1 (0.56) | KDM1AMAPTKDM4EALDH1A1MAPK1 | |
| SCHEMBL14113373 | 0.73 | MAPT (0.50) | KDM1AMAPTKDM4EALDH1A1MAPK1 | |
| SCHEMBL5574408 | 0.72 | KIF11 (0.53) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL15964268 | 0.72 | KDM4E (0.56) | MAPTKDM4EALDH1A1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820989-A1 | IMIDAZOLE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1998-01-28 | — | — | EP | disclosed |