Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548916 | 0.81 | ALDH1A1 (0.44) | ADORA1HSD17B10ALOX15KDM4EALDH1A1 | |
| SCHEMBL8544979 | 0.72 | KMT2A (0.34) | MAPTPOLBKDM4EALDH1A1MEN1 | |
| SCHEMBL31111404 | 0.72 | KMT2A (0.34) | MAPTPOLBKDM4EALDH1A1MEN1 | |
| SCHEMBL6254233 | 0.65 | ALDH1A1 (0.68) | ADORA1MAPTHSD17B10KDM4EALDH1A1 | |
| SCHEMBL10551506 | 0.64 | ERN1 (0.45) | MAPTHSD17B10KDM4EALDH1A1MEN1 | |
| SCHEMBL17795920 | 0.63 | MAPT (0.50) | ADORA1MAPTHSD17B10POLBALOX15 | |
| SCHEMBL845698 | 0.63 | AXL (0.37) | ADORA1ALDH1A1KMT2ANPSR1ADORA2A | |
| SCHEMBL1028588 | 0.62 | MAPT (0.45) | ADORA1MAPTHSD17B10POLBALOX15 | |
| SCHEMBL12679799 | 0.62 | KDM4E (0.55) | ADORA1MAPTHSD17B10POLBALOX15 | |
| SCHEMBL7395814 | 0.62 | ERN1 (0.43) | ADORA1MAPTHSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702003-B1 | Process for preparing 2-halogenpyridinaldehydes | BAYER AG (DE) | 1998-06-17 | — | — | EP | disclosed |
| US-5708180-A | CYCLIZATION OF UNSATURATED NITRILE, AMIDE OR OXIME | BAYER AKTIENGESELLSCHAFT (DE) | 1998-01-13 | — | — | US | disclosed |
| EP-0702003-A2 | Process for preparing 2-halogenpyridinaldehydes and new 2-halogenpyridinaldehydes | BAYER AG (DE) | 1996-03-20 | — | — | EP | disclosed |