Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8543101 | 0.99 | KMT2A (0.49) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8545816 | 0.85 | KMT2A (0.46) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL11518684 | 0.85 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8550542 | 0.84 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL8813396 | 0.78 | MEN1 (0.57) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8815575 | 0.76 | KMT2A (0.68) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8816107 | 0.76 | L3MBTL1 (0.52) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL8814626 | 0.75 | KMT2A (0.67) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8812987 | 0.75 | L3MBTL1 (0.51) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL8814480 | 0.74 | MAPT (0.55) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |