Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540087 | 0.89 | RARB (0.42) | RARBRARAHDAC1HDAC2HDAC3 | |
| SCHEMBL8545577 | 0.86 | RARB (0.41) | RARBRARAHDAC1HDAC2HDAC3 | |
| SCHEMBL8541991 | 0.83 | RARB (0.39) | RARBRARAHDAC1HDAC2HDAC3 | |
| SCHEMBL7558866 | 0.79 | RARB (0.43) | RARBRARAHDAC1HDAC2HDAC3 | |
| SCHEMBL9129539 | 0.77 | RARB (0.40) | RARBRARAHDAC1HDAC2HDAC3 | |
| SCHEMBL7561627 | 0.75 | LTA4H (0.45) | RARBRARAHDAC1HDAC2HDAC3 | |
| SCHEMBL8545316 | 0.75 | RARB (0.44) | RARBRARAHDAC1HDAC2HDAC3 | |
| SCHEMBL8544730 | 0.73 | RARB (0.41) | RARBRARAHDAC1HDAC2NPSR1 | |
| SCHEMBL9122525 | 0.72 | RARB (0.52) | RARBRARATSHRFAAH | |
| SCHEMBL8542604 | 0.71 | PRSS1 (0.42) | RARBRARAHDAC1HDAC2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736078-B1 | CHIRAL LIQUID CRYSTAL COMPOUNDS HAVING A PERFLUOROETHER TERMINAL PORTION | MINNESOTA MINING & MFG (US) | 1998-06-24 | — | — | EP | disclosed |