Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7561627 | 0.82 | LTA4H (0.45) | RARBHDAC3HDAC1HDAC2RARA | |
| SCHEMBL7558866 | 0.79 | RARB (0.43) | RARBHDAC3HDAC1HDAC2RARA | |
| SCHEMBL8542604 | 0.79 | PRSS1 (0.42) | RARBHDAC3HDAC1HDAC2RARA | |
| SCHEMBL8545577 | 0.78 | RARB (0.41) | RARBHDAC3HDAC1HDAC2RARA | |
| SCHEMBL8540087 | 0.76 | RARB (0.42) | RARBHDAC3HDAC1HDAC2RARA | |
| SCHEMBL8541991 | 0.76 | RARB (0.39) | RARBHDAC3HDAC1HDAC2RARA | |
| SCHEMBL8542044 | 0.75 | RARB (0.46) | RARBRARATSHRPLA2G4BSMN1; SMN2 | |
| SCHEMBL8545227 | 0.75 | RARB (0.40) | RARBHDAC3HDAC1HDAC2RARA | |
| SCHEMBL7558883 | 0.74 | LTA4H (0.37) | RARBHDAC3HDAC1HDAC2RARA | |
| SCHEMBL8544730 | 0.73 | RARB (0.41) | RARBHDAC1HDAC2RARATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736078-B1 | CHIRAL LIQUID CRYSTAL COMPOUNDS HAVING A PERFLUOROETHER TERMINAL PORTION | MINNESOTA MINING & MFG (US) | 1998-06-24 | — | — | EP | disclosed |
| US-5474705-A | Electrooptical displays | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-12-12 | — | — | US | disclosed |