Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.60 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.58 |
| ▸ | CTSL | P07711 | 2/20 | 0.56 |
| ▸ | TACR1 | P25103 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | PLAU | P00749 | 2/20 | 0.49 |
| ▸ | PLAT | P00750 | 2/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633246 | 1.00 | TRPM8 (0.60) | TRPM8CTRB1CTSLTACR1CTSB | |
| SCHEMBL9633645 | 1.00 | TRPM8 (0.60) | TRPM8CTRB1CTSLTACR1CTSB | |
| SCHEMBL7414480 | 0.90 | TRPM8 (0.61) | TRPM8CTRB1CTSLTACR1CTSB | |
| SCHEMBL6350990 | 0.90 | TRPM8 (0.61) | TRPM8CTRB1CTSLTACR1CTSB | |
| SCHEMBL7430937 | 0.90 | TRPM8 (0.61) | TRPM8CTRB1CTSLTACR1CTSB | |
| SCHEMBL7245549 | 0.90 | TRPM8 (0.61) | TRPM8CTRB1CTSLTACR1CTSB | |
| SCHEMBL7418088 | 0.90 | TRPM8 (0.61) | TRPM8CTRB1CTSLTACR1CTSB | |
| SCHEMBL9633578 | 0.88 | TRPM8 (0.52) | TRPM8CTRB1CTSLCTSBCTSS | |
| SCHEMBL7418811 | 0.87 | TRPM8 (0.69) | TRPM8CTRB1CTSLTACR1CTSB | |
| SCHEMBL8163494 | 0.87 | TRPM8 (0.69) | TRPM8CTRB1CTSLTACR1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873308-A1 | O-CARBAMOYL-PHENYLALANINOL COMPOUNDS, THEIR PHARMACEUTICALLY USEFUL SALTS AND PROCESS FOR PREPARING THE SAME | SK Corporation (KR) | 1998-10-28 | — | — | EP | disclosed |
| WO-1998015526-A1 | O-CARBAMOYL-PHENYLALANINOL COMPOUNDS, THEIR PHARMACEUTICALLY USEFUL SALTS AND PROCESS FOR PREPARING THE SAME | SK CORPORATION (KR) | 1998-04-16 | — | — | WO | disclosed |