Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 6/20 | 0.50 |
| ▸ | NR1D1 | P20393 | 10/20 | 0.45 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8541086 | 0.92 | TBXAS1 (0.58) | TBXAS1NR1D1 | |
| SCHEMBL8544727 | 0.86 | TBXAS1 (0.52) | TBXAS1 | |
| SCHEMBL8541177 | 0.85 | TBXAS1 (0.54) | TBXAS1NR1D1LTA4H | |
| SCHEMBL8541450 | 0.83 | TRPM5 (0.41) | TBXAS1TRPM5LTA4H | |
| SCHEMBL8544695 | 0.81 | TRPM5 (0.40) | TBXAS1TRPM5LTA4H | |
| SCHEMBL8585361 | 0.81 | TBXAS1 (0.51) | TBXAS1NR1D1LTA4H | |
| SCHEMBL8542535 | 0.78 | TBXAS1 (0.60) | TBXAS1NR1D1 | |
| SCHEMBL8542531 | 0.77 | TBXAS1 (0.50) | TBXAS1NR1D1LTA4H | |
| SCHEMBL8538814 | 0.76 | TBXAS1 (0.63) | TBXAS1 | |
| SCHEMBL8541869 | 0.76 | TBXAS1 (0.62) | TBXAS1NR1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0715627-B1 | INDOLE DERIVATIVES AS THROMBOXANE A2 ANTAGONISTS | PFIZER LTD (GB) | 1998-09-09 | — | — | EP | claimed |