Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.44 |
| ▸ | ACHE | P22303 | 7/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544321 | 0.91 | BCHE (0.46) | BCHEACHEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8545791 | 0.88 | IGF1R (0.42) | BCHEACHEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8549310 | 0.88 | ADORA2A (0.44) | BCHEACHEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8543400 | 0.85 | BCHE (0.44) | BCHEACHEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8545486 | 0.85 | MEN1 (0.48) | BCHEACHEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8544712 | 0.84 | ACHE (0.49) | BCHEACHEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8545799 | 0.84 | ACHE (0.43) | BCHEACHEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8543857 | 0.83 | ACHE (0.44) | BCHEACHEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8545134 | 0.83 | KDM4E (0.50) | BCHEACHEKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8547014 | 0.83 | ACHE (0.44) | BCHEACHEKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179100-A | Analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-01-12 | — | — | US | claimed |
| EP-0560231-B1 | Pyrazolo(3,4-a)acridine derivatives as analgesics | HOECHST MARION ROUSSEL INC (US) | 1998-06-03 | — | — | EP | disclosed |
| EP-0560231-A1 | Pyrazolo(3,4-a)acridine derivatives as analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5179100-A | Analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-01-12 | — | — | US | disclosed |