Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | WNT3A | P56704 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7901165 | 0.91 | MAOB (0.46) | NPC1RAB9ACTNNB1WNT3AMAOB | |
| SCHEMBL8543419 | 0.86 | MAOB (0.55) | MAOB | |
| SCHEMBL8545446 | 0.84 | MAOB (0.46) | NPC1RAB9AMAOBHPGDALDH1A1 | |
| SCHEMBL8551278 | 0.80 | MAOB (0.52) | MAOB | |
| SCHEMBL8546264 | 0.80 | MAOB (0.51) | MAOB | |
| SCHEMBL8546321 | 0.79 | GAA (0.45) | NPC1RAB9AHPGD | |
| SCHEMBL8549185 | 0.79 | NR4A2 (0.54) | NPC1RAB9AMAOBALDH1A1HTT | |
| SCHEMBL8546084 | 0.79 | NR4A2 (0.52) | NPC1RAB9AMAOB | |
| SCHEMBL8551050 | 0.76 | MAOB (0.48) | MAOB | |
| SCHEMBL8548524 | 0.76 | MAOB (0.50) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |