Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7907477 | 0.92 | PARP14 (0.44) | GAAHPGDSPHK2SPHK1PARP14 | |
| SCHEMBL7907473 | 0.92 | PARP14 (0.44) | GAAHPGDSPHK2SPHK1PARP14 | |
| SCHEMBL8543419 | 0.86 | MAOB (0.55) | NR4A2MEN1KMT2A | |
| SCHEMBL8546324 | 0.84 | PARP14 (0.44) | GAAHPGDSPHK2SPHK1PARP14 | |
| SCHEMBL8546264 | 0.83 | MAOB (0.51) | NR4A2HTR1AADRA2ADRD1SLC6A2 | |
| SCHEMBL8549880 | 0.83 | MAOB (0.51) | NR4A2MEN1KMT2A | |
| SCHEMBL8551278 | 0.81 | MAOB (0.52) | NR4A2MEN1KMT2A | |
| SCHEMBL8549185 | 0.80 | NR4A2 (0.54) | NPC1RAB9ANR4A2MEN1KMT2A | |
| SCHEMBL8545445 | 0.79 | NPC1 (0.46) | HPGDNPC1RAB9A | |
| SCHEMBL8546084 | 0.79 | NR4A2 (0.52) | NPC1RAB9ANR4A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728128-B1 | SUBSTITUTED PHENYL COMPOUNDS | RHONE POULENC RORER LTD (GB) | 1998-09-16 | — | — | EP | claimed |