Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.51 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20239626 | 0.89 | TDP1 (0.48) | MAPTBRD4FYNTP53EGLN2 | |
| SCHEMBL5598135 | 0.86 | STAT3 (0.47) | MAPTPTGS2FYNSTAT3L3MBTL1 | |
| SCHEMBL17372934 | 0.81 | MAPT (0.53) | MAPTL3MBTL1MAPK1HSD17B10 | |
| SCHEMBL5597739 | 0.79 | BACE1 (0.46) | MAPTFYNTP53STAT3L3MBTL1 | |
| SCHEMBL6693299 | 0.78 | ATM (0.55) | MAPTPTGS2STAT3DYRK1AMAPK1 | |
| SCHEMBL14458205 | 0.77 | MAPT (0.46) | MAPTTP53EGLN2L3MBTL1MAPK1 | |
| SCHEMBL24314980 | 0.76 | ALDH1A3 (0.58) | MAPTALDH1A3SQORBRD4NPY5R | |
| SCHEMBL30610970 | 0.76 | ALDH1A3 (0.58) | MAPTALDH1A3SQORBRD4NPY5R | |
| SCHEMBL5597719 | 0.75 | ESR2 (0.54) | MAPTFYNHSD17B10 | |
| SCHEMBL5385380 | 0.75 | GABRG2 (0.51) | NPY5REGLN2CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1092186-C | Preparation method of 1, 2-dimethyl-3, 5-diaryl pyrazolium methylsulfate | BASF AG (DE) | 2002-10-09 | — | — | CN | disclosed |
| US-5847154-A | Method of preparing 1,2-dimethyl-3,5-diarylpyrazolium methylsulfates | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| CN-1192734-A | Preparation method of 1, 2-dimethyl-3, 5-diaryl pyrazolium methylsulfate | BASF AG (DE) | 1998-09-09 | — | — | CN | disclosed |