Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 3/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29860013 | 0.89 | KIT (0.41) | KITPDGFRAFGFR3BCHEACHE | |
| SCHEMBL27118380 | 0.89 | ACHE (0.39) | BCHEACHEKDM4EHPGDLMNA | |
| SCHEMBL8390257 | 0.87 | KIT (0.42) | KITPDGFRAFGFR3BCHEACHE | |
| SCHEMBL24277165 | 0.87 | KDM4E (0.39) | BCHEACHEKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL29445057 | 0.87 | KDM4E (0.39) | BCHEACHEKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL8545879 | 0.85 | GAA (0.47) | KITPDGFRAFGFR3GAAKDM4E | |
| SCHEMBL24276906 | 0.85 | KDM4E (0.44) | GAAKDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL8546738 | 0.85 | BCHE (0.58) | BCHEACHEGAAKDM4EHPGD | |
| SCHEMBL29445130 | 0.85 | BCHE (0.58) | BCHEACHEGAAKDM4EHPGD | |
| Dimethylamine SCHEMBL8546032 | 0.84 | KIT (0.44) | KITPDGFRAFGFR3BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591058-B1 | Ellipticine derivatives with antitumor activity | ADIR (FR) | 1998-06-03 | — | — | EP | disclosed |
| EP-0591058-A1 | Ellipticine derivatives with antitumor activity | ADIR ET COMPAGNIE (FR) | 1994-04-06 | — | — | EP | disclosed |