Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | KRAS | P01116 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.44 |
| ▸ | TUBB | P07437 | 3/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8544659 | 0.99 | CYP19A1 (0.49) | CYP19A1TUBB1CA1CA2KRAS | |
| SCHEMBL8544393 | 0.85 | USP2 (0.57) | TUBB1CA1CA2TSHRKDM4E | |
| SCHEMBL8547594 | 0.84 | MAPT (0.55) | SMN1; SMN2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL8546912 | 0.81 | MEN1 (0.57) | SMN1; SMN2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL8550809 | 0.78 | METAP2 (0.46) | KDM4EMEN1KMT2A | |
| SCHEMBL8812152 | 0.77 | CA1 (0.45) | CYP19A1TUBB1CA1CA2KRAS | |
| SCHEMBL8550168 | 0.76 | KMT2A (0.54) | SMN1; SMN2KDM4EALDH1A1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL8812351 | 0.76 | CA1 (0.44) | CYP19A1TUBB1CA1CA2KRAS | |
| SCHEMBL8546969 | 0.76 | SMN1; SMN2 (0.51) | TUBB1KRASTUBB4ATUBBTUBA3C | |
| Hydrochloric Acid SCHEMBL8546948 | 0.75 | KMT2A (0.53) | SMN1; SMN2KDM4EALDH1A1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |