Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | G6PD | P11413 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8546948 | 0.99 | KMT2A (0.53) | KMT2AL3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8549831 | 0.93 | LMNA (0.53) | KMT2AL3MBTL1LMNAHTTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8548333 | 0.92 | LMNA (0.52) | KMT2AL3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8544987 | 0.78 | ALDH1A1 (0.49) | KMT2AL3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL709246 | 0.78 | TDP1 (0.60) | KMT2AL3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL7823257 | 0.77 | ALDH1A1 (0.61) | KMT2AL3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL969334 | 0.76 | TDP1 (0.59) | KMT2AL3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8545646 | 0.76 | CYP19A1 (0.50) | KMT2AL3MBTL1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL708387 | 0.75 | LMNA (0.58) | KMT2AL3MBTL1LMNAHTTSMN1; SMN2 | |
| SCHEMBL8546912 | 0.75 | MEN1 (0.57) | KMT2ALMNASMN1; SMN2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |