⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549053 | 0.91 | AGTR1 (0.39) | — | |
| SCHEMBL9663216 | 0.91 | AGTR1 (0.50) | — | |
| SCHEMBL9429563 | 0.90 | AGTR1 (0.47) | — | |
| SCHEMBL9309893 | 0.90 | AGTR1 (0.48) | — | |
| SCHEMBL8545036 | 0.89 | — | — | |
| SCHEMBL9429521 | 0.88 | — | — | |
| SCHEMBL9310333 | 0.88 | AGTR1 (0.55) | — | |
| SCHEMBL8548665 | 0.87 | AGTR1 (0.47) | — | |
| SCHEMBL9308880 | 0.85 | AGTR1 (0.46) | — | |
| SCHEMBL8957280 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514198-B1 | 1H-Imidazol-1-yl-methyl benzofuran derivatives with the imidazolyl moiety being substituted by a cycloalkyl group | GLAXO GROUP LTD (GB) | 1998-08-05 | — | — | EP | disclosed |
| US-5498722-A | HYPOTENSIVES | GLAXO GROUP (GB) | 1996-03-12 | — | — | US | disclosed |
| US-5332831-A | Angiotensin antagonist | GLAXO GROUP LIMITED (GB) | 1994-07-26 | — | — | US | disclosed |
| WO-1992020674-A1 | 1H-IMIDAZOL-1-YL-METHYL BENZOFURAN DERIVATIVES, WITH THE IMIDAZOLYL MOIETY BEING SUBSTITUTED BY A CYCLOALKYL GROUP | GLAXO GROUP LIMITED (GB) | 1992-11-26 | — | — | WO | disclosed |