Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | DHODH | Q02127 | 10/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3156280 | 0.88 | PDE10A (0.54) | PDE10AKMT2ATSHRDHODHMEN1 | |
| SCHEMBL30682020 | 0.86 | PDE10A (0.60) | PDE10AKMT2ATSHRDHODHMEN1 | |
| SCHEMBL7533563 | 0.86 | PDE10A (0.60) | PDE10AKMT2ATSHRDHODHMEN1 | |
| SCHEMBL13957825 | 0.82 | PDE10A (1.00) | PDE10AKMT2ATSHRDHODHMEN1 | |
| SCHEMBL15487114 | 0.81 | DHODH (0.63) | PDE10AKMT2ATSHRDHODHMEN1 | |
| SCHEMBL14106730 | 0.81 | PDE10A (0.72) | PDE10AKMT2ATSHRDHODHMEN1 | |
| SCHEMBL2313999 | 0.79 | MAOA (0.55) | PDE10AKMT2ATSHRDHODHMEN1 | |
| SCHEMBL1581468 | 0.78 | PDE10A (1.00) | PDE10AKMT2ATSHRDHODHLMNA | |
| SCHEMBL27943843 | 0.77 | TDP1 (0.52) | PDE10AKMT2ATSHRMEN1HTT | |
| SCHEMBL27446591 | 0.77 | DHODH (0.54) | PDE10AKMT2ATSHRDHODHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109467549-B | Quinoline-substituted chalcone compound, preparation method and application thereof | 中国药科大学 | 2021-02-09 | — | — | CN | disclosed |
| EP-0714393-B1 | THIAZOLES AS ANTIVIRAL | PFIZER (US) | 1998-09-23 | — | — | EP | disclosed |