Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | C3AR1 | Q16581 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546968 | 0.87 | F10 (0.57) | GRIN2BFAAHPOLBCPB1SMN1; SMN2 | |
| SCHEMBL8539166 | 0.85 | GRIN2B (0.54) | GRIN2BFAAHPOLBCPB1SMN1; SMN2 | |
| SCHEMBL8541444 | 0.84 | GRIN2B (0.53) | GRIN2BFAAHPOLBCPB1SMN1; SMN2 | |
| SCHEMBL8541896 | 0.84 | FAAH (0.56) | GRIN2BFAAHPOLBCPB1ALDH1A1 | |
| SCHEMBL10417640 | 0.82 | GNAI3 (0.55) | FAAHSMN1; SMN2F10L3MBTL1 | |
| SCHEMBL8697813 | 0.82 | NPC1 (0.51) | GRIN2BSMN1; SMN2NPC1TDP1MEN1 | |
| SCHEMBL8541622 | 0.81 | GRIN2B (0.52) | GRIN2B | |
| SCHEMBL8545032 | 0.81 | FAAH (0.52) | GRIN2BFAAHPOLBCPB1ALDH1A1 | |
| SCHEMBL8545094 | 0.81 | F10 (0.57) | GRIN2BFAAHPOLBALDH1A1KDM4E | |
| SCHEMBL8544549 | 0.78 | GRIN2B (0.53) | GRIN2BFAAHPOLBCPB1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705258-B1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1998-12-30 | — | — | EP | disclosed |
| EP-0705258-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | Knoll AG (DE) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000507-A1 | AZOLYL-CYCLIC AMINE DERIVATIVES WITH IMMUNOMODULATORY ACTIVITY | KNOLL AG (DE) | 1995-01-05 | — | — | WO | disclosed |