Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545195 | 0.92 | ALDH1A1 (0.47) | — | |
| SCHEMBL8542707 | 0.87 | KDM4E (0.38) | MAP2 | |
| SCHEMBL8541345 | 0.87 | EDNRB (0.38) | — | |
| SCHEMBL8543925 | 0.87 | PDE5A (0.41) | — | |
| SCHEMBL8543816 | 0.86 | EDNRB (0.42) | — | |
| SCHEMBL8540271 | 0.85 | — | — | |
| SCHEMBL8546149 | 0.85 | RXRA (0.41) | — | |
| SCHEMBL8540287 | 0.84 | MRGPRX4 (0.41) | — | |
| SCHEMBL8541997 | 0.84 | EDNRB (0.44) | — | |
| SCHEMBL8545082 | 0.84 | CHEK2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800389-A4 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1998-04-29 | — | — | EP | claimed |
| EP-0800389-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-10-15 | — | — | EP | claimed |
| WO-1996018393-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-06-20 | — | — | WO | claimed |