Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543655 | 0.91 | ITGB3 (0.54) | MAOAMAOBITGB3ITGA2B | |
| SCHEMBL8544276 | 0.89 | MAOA (0.51) | ALOX5MAOAMAOBITGB3ITGA2B | |
| SCHEMBL8550037 | 0.88 | ITGB3 (0.53) | MAOAMAOBITGB3ITGA2B | |
| SCHEMBL8547044 | 0.87 | ITGB3 (0.53) | MAOAMAOBITGB3ITGA2B | |
| SCHEMBL8548776 | 0.85 | ITGB3 (0.53) | ALOX5MAOAMAOBITGB3ITGA2B | |
| SCHEMBL8550145 | 0.82 | ITGB3 (0.56) | ITGB3ITGA2B | |
| SCHEMBL8545868 | 0.82 | ITGB3 (0.51) | ITGB3ITGA2B | |
| SCHEMBL8542223 | 0.82 | ITGB3 (0.54) | ITGB3ITGA2BS1PR1 | |
| SCHEMBL9425224 | 0.82 | ITGB3 (0.51) | ALOX5ITGB3ITGA2B | |
| SCHEMBL8545572 | 0.82 | ITGB3 (0.51) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526402-B1 | Heteroaryl substituted hydroxylamine derivatives as lipoxygenase inhibitors | CIBA GEIGY AG (CH) | 1998-01-21 | — | — | EP | disclosed |
| US-5350761-A | Lipoxygenase inhibitors as antiinflammatory agents and antiallergens | CIBA-GEIGY CORPORATION (US) | 1994-09-27 | — | — | US | disclosed |
| US-5334600-A | Lipoxygenase inhibitors | CIBA-GEIGY CORPORATION (US) | 1994-08-02 | — | — | US | disclosed |
| US-5260316-A | Lipoxygenase inhibitor | CIBA-GEIGY CORPORATION (US) | 1993-11-09 | — | — | US | disclosed |
| EP-0526402-A1 | Heteroaryl substituted hydroxylamine derivatives as lipoxygenase inhibitors | CIBA-GEIGY AG (CH) | 1993-02-03 | — | — | EP | disclosed |