Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545747 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CYP2A6SMN1; SMN2LMNAMAPT | |
| SCHEMBL8545742 | 1.00 | ALDH1A1 (0.52) | ALDH1A1CYP2A6SMN1; SMN2LMNAMAPT | |
| SCHEMBL28529733 | 0.90 | ALDH1A1 (0.53) | ALDH1A1CYP2A6SMN1; SMN2LMNAMAPT | |
| SCHEMBL7190561 | 0.88 | ALDH1A1 (0.46) | ALDH1A1CYP2A6SMN1; SMN2LMNAMAPT | |
| SCHEMBL6689787 | 0.88 | ALDH1A1 (0.50) | ALDH1A1CYP2A6SMN1; SMN2LMNAMAPT | |
| SCHEMBL7190568 | 0.88 | ALDH1A1 (0.46) | ALDH1A1CYP2A6SMN1; SMN2LMNAMAPT | |
| SCHEMBL2559715 | 0.86 | ALDH1A1 (0.52) | ALDH1A1CYP2A6SMN1; SMN2LMNAMAPT | |
| SCHEMBL7680410 | 0.83 | KMT2A (0.45) | ALDH1A1CYP2A6SMN1; SMN2LMNAMAPT | |
| SCHEMBL7680402 | 0.83 | KMT2A (0.45) | ALDH1A1CYP2A6SMN1; SMN2LMNAMAPT | |
| SCHEMBL9522631 | 0.83 | PPARG (0.55) | ALDH1A1CYP2A6SMN1; SMN2KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |
| EP-0533933-A1 | BISHETEROCYCLIC COMPOUND | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |