Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.50 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545747 | 0.88 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL8545975 | 0.88 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL8545742 | 0.88 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL28529733 | 0.83 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL9860949 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDLMNAKMT2A | |
| SCHEMBL9860945 | 0.82 | ALDH1A1 (0.55) | ALDH1A1MAPTHPGDLMNAKMT2A | |
| SCHEMBL25192419 | 0.81 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL7190568 | 0.81 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL7190561 | 0.81 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPTHPGDLMNA | |
| SCHEMBL8027229 | 0.81 | CHRNB2 (0.49) | ALDH1A1MAPTLMNAKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004113266-A1 | DERIVATIVES OF PHENYLALKYL AND PHENOXYALKYL ACIDS FOR THE TREATMENT OF THE HYPERGLYCAEMIA AND HYPERTRIGLYCERIDAEMIA AND TYPE 2 DIABETES AND PROCESS FOR PREPARING THEM | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2004-12-29 | — | — | WO | disclosed |