Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | PTAFR | P25105 | 3/20 | 0.32 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543077 | 0.99 | BCHE (0.68) | BCHESLC6A2ACHEPTAFRASAH1 | |
| SCHEMBL8544657 | 0.88 | BCHE (0.72) | BCHESLC6A2ACHE | |
| SCHEMBL8543976 | 0.87 | SLC6A2 (0.54) | BCHESLC6A2 | |
| SCHEMBL8546112 | 0.87 | BCHE (0.52) | BCHESLC6A2S1PR1ASAH1NAMPT | |
| SCHEMBL8544814 | 0.86 | SLC6A2 (0.55) | BCHESLC6A2 | |
| SCHEMBL8544200 | 0.86 | BCHE (0.53) | BCHESLC6A2S1PR1ASAH1NAMPT | |
| Hydrochloric Acid SCHEMBL8543736 | 0.85 | BCHE (0.52) | BCHESLC6A2S1PR1ASAH1NAMPT | |
| SCHEMBL8537919 | 0.82 | BCHE (0.94) | BCHEACHE | |
| SCHEMBL8543791 | 0.80 | BCHE (1.00) | BCHESLC6A2ACHE | |
| SCHEMBL8544179 | 0.79 | BCHE (0.64) | BCHESLC6A2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468401-B1 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0468401-A2 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-01-29 | — | — | EP | disclosed |