Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | GPX4 | P36969 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8541330 | 0.99 | BCHE (0.34) | BCHEKDM4CS1PR1PTGDR2ICMT | |
| SCHEMBL8544202 | 0.97 | BCHE (0.36) | BCHEKDM4CS1PR1PTGDR2KDM6B | |
| Hydrochloric Acid SCHEMBL8543739 | 0.97 | BCHE (0.35) | BCHEKDM4CS1PR1KDM6B | |
| SCHEMBL8539192 | 0.86 | ORAI1 (0.33) | BCHEKDM4C | |
| SCHEMBL8544184 | 0.85 | BCHE (0.43) | BCHEKDM4CPTGDR2ICMTNPC1 | |
| SCHEMBL8543079 | 0.82 | BCHE (0.45) | BCHEKDM4CPTGDR2ICMTKDM6B | |
| SCHEMBL9738702 | 0.80 | BCHE (0.48) | BCHE | |
| Hydrochloric Acid SCHEMBL9671922 | 0.79 | BCHE (0.47) | BCHE | |
| SCHEMBL9738844 | 0.78 | BCHE (0.51) | BCHE | |
| Hydrochloric Acid SCHEMBL9671993 | 0.77 | BCHE (0.50) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468401-B1 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0468401-A2 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-01-29 | — | — | EP | disclosed |