Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | QPCT | Q16769 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8543739 | 0.99 | BCHE (0.35) | BCHEKDM4CKDM6BS1PR1SLC6A2 | |
| SCHEMBL8546113 | 0.97 | BCHE (0.34) | BCHEKDM4CKDM6BS1PR1PTGDR2 | |
| Hydrochloric Acid SCHEMBL8541330 | 0.97 | BCHE (0.34) | BCHEKDM4CKDM6BS1PR1PTGDR2 | |
| SCHEMBL8539192 | 0.88 | ORAI1 (0.33) | BCHEKDM4CITGB3ITGAVACHE | |
| SCHEMBL8543079 | 0.84 | BCHE (0.45) | BCHEKDM4CKDM6BACHEPTGDR2 | |
| SCHEMBL8544184 | 0.82 | BCHE (0.43) | BCHEKDM4CKDM6BACHEPTGDR2 | |
| SCHEMBL9738844 | 0.80 | BCHE (0.51) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL9671993 | 0.79 | BCHE (0.50) | BCHEACHE | |
| SCHEMBL8539327 | 0.79 | BCHE (0.49) | BCHEITGB3ITGAVACHE | |
| SCHEMBL8546208 | 0.79 | MAPT (0.36) | SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468401-B1 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0468401-A2 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-01-29 | — | — | EP | disclosed |