Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGAV | P06756 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8544202 | 0.88 | BCHE (0.36) | BCHEKDM4CITGB3ITGAVACHE | |
| Hydrochloric Acid SCHEMBL8543739 | 0.88 | BCHE (0.35) | BCHEKDM4CITGB3ITGAVACHE | |
| SCHEMBL8546113 | 0.86 | BCHE (0.34) | BCHEKDM4C | |
| Hydrochloric Acid SCHEMBL8541330 | 0.85 | BCHE (0.34) | BCHEKDM4C | |
| SCHEMBL8544660 | 0.84 | BCHE (0.43) | ORAI1BCHEKDM4CACHE | |
| SCHEMBL8546208 | 0.81 | MAPT (0.36) | MAPT | |
| Hydrochloric Acid SCHEMBL8539622 | 0.80 | MAPT (0.35) | MAPT | |
| SCHEMBL8539327 | 0.80 | BCHE (0.49) | BCHEMAPTITGB3ITGAVACHE | |
| SCHEMBL9738844 | 0.77 | BCHE (0.51) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL9671993 | 0.76 | BCHE (0.50) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0468401-B1 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1998-09-16 | — | — | EP | disclosed |
| EP-0468401-A2 | 1-(Substituted pyridinylamino)-1H-indol-5-yl substituted carbamates, a process and intermediates for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-01-29 | — | — | EP | disclosed |