Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | LOX | P28300 | 1/20 | 0.32 |
| ▸ | TYMS | P04818 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855592 | 0.79 | ALDH1A1 (0.38) | ALOX15TDP1TYMSTSHRALDH1A1 | |
| SCHEMBL30451169 | 0.79 | TSHR (0.38) | ALOX15TDP1TSHR | |
| SCHEMBL26183091 | 0.79 | TSHR (0.38) | ALOX15TDP1TSHR | |
| SCHEMBL31419795 | 0.79 | TDP1 (0.34) | ALOX15TDP1MAOAMAOBTSHR | |
| SCHEMBL19585826 | 0.79 | TDP1 (0.34) | ALOX15TDP1MAOAMAOBTSHR | |
| SCHEMBL854471 | 0.79 | TSHR (0.38) | ALOX15TDP1TSHR | |
| SCHEMBL28283847 | 0.76 | ALOX15 (0.32) | ALOX15TDP1 | |
| SCHEMBL127075 | 0.76 | ALOX15 (0.39) | ALOX15TDP1TYMSTSHRALDH1A1 | |
| SCHEMBL18016210 | 0.75 | NPC1 (0.37) | ALOX15TDP1ALDH1A1 | |
| SCHEMBL30523205 | 0.74 | ALOX15 (0.37) | ALOX15TDP1TYMSALOX5TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405995-A | Difluorophthalic compounds and their preparation | OCCIDENTAL CHEMICAL CORPORATION (US) | 1995-04-11 | — | — | US | claimed |
| US-8604221-B2 | Production method of halogen-substituted phthalide | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-12-10 | — | — | US | disclosed |
| US-20120142946-A1 | PRODUCTION METHOD OF HALOGEN-SUBSTITUTED PHTHALIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-06-07 | — | — | US | disclosed |
| EP-2433933-A1 | PRODUCTION METHOD OF HALOGEN-SUBSTITUTED PHTHALIDE | Sumitomo Chemical Company, Limited (JP) | 2012-03-28 | — | — | EP | disclosed |
| US-5405995-A | Difluorophthalic compounds and their preparation | OCCIDENTAL CHEMICAL CORPORATION (US) | 1995-04-11 | — | — | US | disclosed |
| US-5405995-A | Difluorophthalic compounds and their preparation | OCCIDENTAL CHEMICAL CORPORATION (US) | 1995-04-11 | — | — | US | disclosed |
| EP-0128453-B1 | PROCESS FOR PREPARING FLUOROPHTHALIC-ACID IMIDES | BASF Aktiengesellschaft (DE) | 1989-10-11 | — | — | EP | disclosed |
| US-4680412-A | Preparation of fluorophthalimides | BASF AKTIENGESELLSCHAFT (DE) | 1987-07-14 | — | — | US | disclosed |
| EP-0128453-A2 | Process for preparing fluorophthalic-acid imides | BASF Aktiengesellschaft (DE) | 1984-12-19 | — | — | EP | disclosed |