SCHEMBL8546708

SCHEMBL8546708

Nn1cccc1C(=O)CCCCl

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
MAP3K14 Q99558 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
MAPT P10636 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.31
GAA P10253 1/20 0.31
MAOB P27338 1/20 0.30
HDAC3 O15379 1/20 0.30
HDAC4 P56524 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC10 Q969S8 1/20 0.30
HDAC11 Q96DB2 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30
HDAC9 Q9UKV0 1/20 0.30
HDAC5 Q9UQL6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14625999 0.82 GSK3B (0.42) LMNAMAP3K14L3MBTL1MAPTKDM4E
SCHEMBL8541004 0.74 MAPT (0.37) LMNAMAP3K14L3MBTL1MAPTKDM4E
SCHEMBL8544645 0.71 POLB (0.37) MAPTTDP1ALDH1A1GAAHDAC3
SCHEMBL782203 0.69
SCHEMBL1269750 0.69
Hydrochloric Acid SCHEMBL28339228 0.67 LMNA (0.43) LMNAMAP3K14L3MBTL1MAPTTDP1
SCHEMBL3827167 0.67
Hydrochloric Acid SCHEMBL3821986 0.66 BAZ2B (0.35) LMNAMAP3K14L3MBTL1TDP1MAOB
SCHEMBL318784 0.66 TDP1 (0.72) LMNAL3MBTL1MAPTTDP1KDM4E
SCHEMBL8308338 0.64 MAOB (0.40) LMNAMAP3K14KDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648764-B1 N-(substituted amino)pyrrole derivatives, preparation process thereof, and herbicidal compositions KUREHA CHEMICAL IND CO LTD (JP) 1998-12-16 EP disclosed
US-5612287-A N-(substituted amino) pyrrole derivatives preparation process thereof, and herbicidal compositions KUREHA KAGAKU KOGYO K.K. (JP) 1997-03-18 US disclosed
US-5604178-A N-(substituted amino)pyrrole derivatives, and herbicidal compositions KUREHA KAGAKU KOGYO K.K. (JP) 1997-02-18 US disclosed
EP-0648764-A1 N-(substituted amino)pyrrole derivatives, preparation process thereof, and herbicidal compositions KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1995-04-19 EP disclosed