SCHEMBL318784

SCHEMBL318784

O=C(CCCCl)c1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.72
MAPT P10636 3/20 0.72
L3MBTL1 Q9Y468 2/20 0.72
LMNA P02545 2/20 0.72
HDAC1 Q13547 5/20 0.64
HDAC8 Q9BY41 5/20 0.64
HDAC3 O15379 1/20 0.64
HDAC4 P56524 1/20 0.64
HDAC7 Q8WUI4 1/20 0.64
HDAC2 Q92769 1/20 0.64
HDAC10 Q969S8 1/20 0.64
HDAC11 Q96DB2 1/20 0.64
HDAC6 Q9UBN7 1/20 0.64
HDAC9 Q9UKV0 1/20 0.64
HDAC5 Q9UQL6 1/20 0.64
NPC1 O15118 1/20 0.62
CASP3 P42574 1/20 0.62
RAB9A P51151 1/20 0.62
SENP8 Q96LD8 1/20 0.62
SENP7 Q9BQF6 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29506825 0.98 TDP1 (0.69) TDP1MAPTL3MBTL1LMNAHDAC1
Ethylene SCHEMBL10973512 0.96 TDP1 (0.67) TDP1MAPTL3MBTL1LMNAHDAC1
Ethylene Glycol SCHEMBL11544664 0.94 TDP1 (0.64) TDP1MAPTL3MBTL1LMNAHDAC1
Acetic Acid SCHEMBL2763001 0.94 L3MBTL1 (0.64) TDP1MAPTL3MBTL1LMNAHDAC1
SCHEMBL2238406 0.94 TDP1 (0.76) TDP1MAPTL3MBTL1LMNAHDAC1
Butane SCHEMBL27573434 0.92 L3MBTL1 (0.62) TDP1MAPTL3MBTL1LMNAHDAC1
SCHEMBL633948 0.92 TDP1 (0.80) TDP1MAPTL3MBTL1LMNAHDAC1
SCHEMBL633401 0.92 TDP1 (0.80) TDP1MAPTL3MBTL1LMNAHDAC1
SCHEMBL2236826 0.92 TDP1 (0.80) TDP1MAPTL3MBTL1LMNAHDAC1
SCHEMBL9035605 0.89 TDP1 (0.58) TDP1MAPTL3MBTL1LMNAHDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106380441-A Synthetic method of fexofenadine intermediate 上海雅本化学有限公司 2017-02-08 CN claimed
WO-2010121022-A1 MONOAMINE REUPTAKE INHIBITORS RESEARCH TRIANGLE INSTITUTE (US) 2010-10-21 WO claimed
EP-0544812-B1 BISPHOSPHONIC ACID DERIVATIVES AS ANTI-ARTHRITIC AGENTS UPJOHN CO (US) 1995-04-05 EP claimed
EP-0004951-A1 N-(3-benzoylpropyl)-spiro-(dihydrobenzofuranpiperidines and -pyrrolidines), derivatives thereof, methods for their preparation and their use for medicines HOECHST AKTIENGESELLSCHAFT (DE) 1979-10-31 EP claimed
US-4025580-A ACYLATION IN PRESENCE OF LEWIS ACID CATALYST; BIODEGRADABLE PACKAGING OWENS-ILLINOIS, INC. (US) 1977-05-24 US claimed
JP-11001455-A None JP disclosed
US-20240334931-A1 NEMATICIDAL COMPOSITION ISHIHARA SANGYO KAISHA, LTD. (JP) 2024-10-10 US disclosed
US-20240287009-A1 AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME INFINEUM INTERNATIONAL LIMITED (GB) 2024-08-29 US disclosed
EP-4410772-A2 AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME Infineum International Limited (GB) 2024-08-07 EP disclosed
CN-118440229-A Amine functional monomers and methods of making the same 英菲诺姆国际有限公司 2024-08-06 CN disclosed
EP-4368023-A1 NEMATOCIDAL COMPOSITION Ishihara Sangyo Kaisha, Ltd. (JP) 2024-05-15 EP disclosed
CN-117479838-A Nematicidal composition 石原产业株式会社 2024-01-30 CN disclosed
US-3979444-A CENTRAL NERVOUS SYSTEM DEPRESSANTS, HYPOTENSIVES THE UPJOHN COMPANY (US) 1976-09-07 US disclosed
US-3966748-A NEUROLEPTIC, ANALGESIC AMERICAN CYANAMID COMPANY (US) 1976-06-29 US disclosed
US-3965257-A DIPHENYL-4-PIPERIDYL-METHANES RICHARDSON-MERRELL INC. (US) 1976-06-22 US disclosed
US-3960961-A 4'-Fluoro-4-{[4-(phenyl)cyclohexyl]amino}butyrophenones and the salts thereof THE UPJOHN COMPANY (US) 1976-06-01 US disclosed
US-3953425-A Azepine indanyl and tetralin butyrophenones THE UPJOHN COMPANY (US) 1976-04-27 US disclosed
US-3947578-A Omega-[4-(3\"-indolyl)-piperidino]-alkyl-arylketones as nevroleptics ROUSSEL UCLAF (FR) 1976-03-30 US disclosed
US-3932429-A Novel azabicyclo octane derivative and process for preparing same TANABE SEIYAKU CO., LTD (JA) 1976-01-13 US disclosed
US-3931197-A ANTIHISTAMINE, ANTIALLERGY, BRONCHODILATOR RICHARDSON-MERRELL INC. (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287009-A1 AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME AMD1, HNMT, MAT1A TDP1 110/4885MAPT 2352/4885L3MBTL1 1448/4885
US-20240334931-A1 NEMATICIDAL COMPOSITION ACHE, UNC119, NACA TDP1 3745/4885MAPT 3132/4885L3MBTL1 324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.