Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 10/20 | 0.43 |
| ▸ | NQO1 | P15559 | 4/20 | 0.35 |
| ▸ | TOP2A | P11388 | 6/20 | 0.33 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.32 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025183 | 0.89 | NQO2 (0.38) | NQO2NQO1TOP2A | |
| SCHEMBL8544353 | 0.88 | NQO2 (0.38) | NQO2NQO1TOP2A | |
| SCHEMBL8539725 | 0.86 | NQO2 (0.33) | NQO2NQO1TOP2AFERMT2EHMT2 | |
| SCHEMBL8546683 | 0.85 | NQO2 (0.52) | NQO2NQO1TOP2AFERMT2 | |
| SCHEMBL9025524 | 0.85 | TOP2A (0.38) | NQO2NQO1TOP2A | |
| SCHEMBL8545959 | 0.85 | NQO2 (0.38) | NQO2NQO1TOP2A | |
| SCHEMBL9024397 | 0.83 | TOP2A (0.40) | NQO2NQO1TOP2A | |
| SCHEMBL9024054 | 0.83 | TOP2A (0.38) | NQO2TOP2A | |
| SCHEMBL9024084 | 0.81 | NQO2 (0.37) | NQO2NQO1TOP2A | |
| SCHEMBL8540653 | 0.81 | NQO2 (0.37) | NQO2NQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487097-B1 | Pyrazoloacridone derivatives | KYOWA HAKKO KOGYO KK (JP) | 1998-10-14 | — | — | EP | disclosed |
| US-5220026-A | Antitumor agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0487097-A1 | Pyrazoloacridone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-05-27 | — | — | EP | disclosed |