Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 4/20 | 0.31 |
| ▸ | MAOA | P21397 | 3/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545884 | 0.89 | CYP19A1 (0.31) | NQO2 | |
| SCHEMBL8548375 | 0.86 | NQO2 (0.40) | NQO2APP | |
| SCHEMBL8543409 | 0.85 | NQO2 (0.43) | NQO2 | |
| SCHEMBL8547162 | 0.82 | CYP19A1 (0.34) | NQO2MAOBALDH1A1 | |
| SCHEMBL8547454 | 0.80 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL8539652 | 0.73 | ERO1A (0.33) | KDM4EALDH1A1MAPK1RECQLKMT2A | |
| SCHEMBL8539725 | 0.71 | NQO2 (0.33) | NQO2TDP1 | |
| SCHEMBL8546612 | 0.70 | HTR2A (0.32) | KMT2A | |
| SCHEMBL8546683 | 0.70 | NQO2 (0.52) | NQO2APP | |
| SCHEMBL9024132 | 0.70 | ALDH1A1 (0.33) | MAOAKDM4EGLAALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487097-B1 | Pyrazoloacridone derivatives | KYOWA HAKKO KOGYO KK (JP) | 1998-10-14 | — | — | EP | disclosed |
| US-5220026-A | Antitumor agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1993-06-15 | — | — | US | disclosed |
| EP-0487097-A1 | Pyrazoloacridone derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-05-27 | — | — | EP | disclosed |