SCHEMBL8547437

SCHEMBL8547437

c1ccc2c(OC3CO3)cccc2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.45
MEN1 O00255 2/20 0.45
RAB9A P51151 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
HTR1B P28222 5/20 0.42
SLC6A4 P31645 4/20 0.40
SLC6A2 P23975 3/20 0.40
SLC6A3 Q01959 3/20 0.40
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 2/20 0.40
KCNA3 P22001 1/20 0.40
HPGD P15428 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
HSD17B10 Q99714 3/20 0.39
PGR P06401 1/20 0.39
GAA P10253 1/20 0.39
PTGS1 P23219 1/20 0.39
MAPK1 P28482 1/20 0.39
HTR1D P28221 1/20 0.39
HRH1 P35367 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20014006 0.85 KMT2A (0.46) KMT2AMEN1RAB9AL3MBTL1HTR1B
SCHEMBL21060606 0.81 MAPT (0.52) KMT2AMEN1RAB9AALDH1A1KDM4E
SCHEMBL19583472 0.81 ALDH1A1 (0.41) KMT2AMEN1SLC6A4SLC6A2SLC6A3
SCHEMBL11057549 0.80 KDM4C (0.44) KMT2AMEN1RAB9AL3MBTL1ALDH1A1
SCHEMBL16902862 0.76 MEN1 (0.51) KMT2AMEN1RAB9AL3MBTL1HTR1B
SCHEMBL8547434 0.74 HTR1B (0.43) KMT2AMEN1RAB9AL3MBTL1HTR1B
SCHEMBL17996084 0.74 ALDH1A1 (0.54) KMT2AMEN1SLC6A4SLC6A2SLC6A3
SCHEMBL15627289 0.73 MCHR1 (0.47) KMT2AMEN1RAB9AL3MBTL1HTR1B
SCHEMBL5026215 0.73 ALDH1A1 (0.62) KMT2AMEN1HTR1BSLC6A4ALDH1A1
SCHEMBL5433989 0.73 ALDH1A1 (0.62) KMT2AMEN1HTR1BSLC6A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760871-B2 Thermosetting resin composition, prepreg, resin sheet, metal foil-clad laminate, and printed wiring board MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-09-19 US disclosed
US-11702504-B2 Resin composition for printed wiring board, prepreg, laminate, metal foil-clad laminate, printed wiring board, and multilayer printed wiring board MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-07-18 US disclosed
US-11702504-B2 Resin composition for printed wiring board, prepreg, laminate, metal foil-clad laminate, printed wiring board, and multilayer printed wiring board MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-07-18 US disclosed
US-20210301071-A1 RESIN COMPOSITION FOR PRINTED WIRING BOARD, PREPREG, LAMINATE, METAL FOIL-CLAD LAMINATE, PRINTED WIRING BOARD, AND MULTILAYER PRINTED WIRING BOARD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-09-30 US disclosed
US-20210147614-A1 THERMOSETTING COMPOSITION, PREPREG, LAMINATE, METAL FOIL-CLAD LAMINATE, PRINTED WIRING BOARD, AND MULTILAYER PRINTED WIRING BOARD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2021-05-20 US disclosed
US-20200325292-A1 RESIN COMPOSITION, PREPREG, LAMINATE, METAL FOIL-CLAD LAMINATE, PRINTED WIRING BOARD, AND MULTILAYER PRINTED WIRING BOARD MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2020-10-15 US disclosed
US-20080032176-A1 Fuel cell separator composition, fuel cell separator, and method for producing the same NICHIAS CORPORATION (JP) 2008-02-07 US disclosed
EP-0467248-B1 Pyrazolopyridine compound and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO (JP) 1998-10-28 EP disclosed
US-5204346-A Cognition activators; analgesics; antidepressants; vasodilation; cardiovascular and urogential disorders; FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-04-20 US disclosed
EP-0467248-A2 Pyrazolopyridine compound and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-01-22 EP disclosed