Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28448067 | 0.75 | ALDH1A1 (0.40) | HTR1BKMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL8547437 | 0.74 | KMT2A (0.45) | HTR1BKMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL16902862 | 0.73 | MEN1 (0.51) | HTR1BKMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL29407118 | 0.73 | HTR1B (0.41) | HTR1BKMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL2456851 | 0.73 | HTR1B (0.41) | HTR1BKMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL15171471 | 0.73 | ALDH1A1 (0.40) | HTR1BKMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL20014006 | 0.72 | KMT2A (0.46) | HTR1BKMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL8547250 | 0.72 | HTR1B (0.51) | HTR1BKMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL7754728 | 0.71 | HTR1B (0.46) | HTR1BALDH1A1KDM4EKCNA3HPGD | |
| Oxirane SCHEMBL11776735 | 0.71 | HTR1B (0.46) | HTR1BKMT2AMEN1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1042730-C | Pyrazolopyridine compound and process for prepn. thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-03-31 | — | — | CN | disclosed |
| EP-0467248-B1 | Pyrazolopyridine compound and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-10-28 | — | — | EP | disclosed |
| US-5204346-A | Cognition activators; analgesics; antidepressants; vasodilation; cardiovascular and urogential disorders; | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-04-20 | — | — | US | disclosed |
| CN-1059143-A | Pyrazolopyridine compound and preparation method thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-03-04 | — | — | CN | disclosed |
| EP-0467248-A2 | Pyrazolopyridine compound and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-01-22 | — | — | EP | disclosed |