SCHEMBL8547718

SCHEMBL8547718

CN(C)/C=N/S(=O)(=O)CCCCCCl

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8547721 1.00 LMNA (0.33) LMNAGAA
SCHEMBL12812539 0.98 LMNA (0.33) LMNAGAA
SCHEMBL13166691 0.92 LMNA (0.34) LMNAGAA
SCHEMBL5784904 0.92 LMNA (0.34) LMNAGAA
SCHEMBL5784908 0.92 LMNA (0.34) LMNAGAA
SCHEMBL12812537 0.83 FAAH (0.42) LMNAGAA
SCHEMBL13166734 0.81 LMNA (0.33) LMNAGAA
SCHEMBL8749378 0.81 LMNA (0.33) LMNAGAA
SCHEMBL12812576 0.79 LMNA (0.33) LMNAGAA
SCHEMBL13166658 0.76 LMNA (0.38) LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5705494-A INDUCED BY ADMINISTERING; COMBAT SIDE EFFECTS OF GLUCOCORTICOIDS ROUSSEL-UCLAF (FR) 1998-01-06 US disclosed
US-5679788-A ANTIESTEROGENIC AGENT ROUSSEL UCLAF (FR) 1997-10-21 US disclosed
EP-0629635-B1 New 19-nor 11-beta-phenoxysulfonamide or 11-beta-phenoxyalkylsulfonylurea steriod derivatives, a process and intermediates for their production and their use as medicaments and pharmaceuticals containing them ROUSSEL UCLAF (FR) 1997-03-19 EP disclosed
US-5556845-A ANTIESTROGEN ROUSSEL UCLAF (FR) 1996-09-17 US disclosed
US-5494907-A ANTIESTROGEN ACTIVITY ROUSSEL UCLAF (FR) 1996-02-27 US disclosed
EP-0629635-A1 New 19-nor 11-beta-phenoxysulfonamide or 11-beta-phenoxyalkylsulfonylurea steriod derivatives, a process and intermediates for their production and their use as medicaments and pharmaceuticals containing them ROUSSEL UCLAF (FR) 1994-12-21 EP disclosed