Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.71 |
| ▸ | LMNA | P02545 | 5/20 | 0.70 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | THRB | P10828 | 1/20 | 0.63 |
| ▸ | NAMPT | P43490 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GALR3 | O60755 | 2/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545052 | 0.89 | MAPT (0.58) | MAPTLMNATP53THRBNAMPT | |
| SCHEMBL7334961 | 0.88 | MAPT (0.62) | MAPTLMNATP53THRBNAMPT | |
| SCHEMBL7360099 | 0.87 | LMNA (0.55) | MAPTLMNATP53THRBNAMPT | |
| SCHEMBL8542813 | 0.82 | F2 (0.73) | MAPTF2NR3C1 | |
| SCHEMBL7324331 | 0.82 | CA12 (0.61) | MAPTLMNATP53THRBMEN1 | |
| SCHEMBL7329347 | 0.81 | KMT2A (0.70) | MAPTLMNATP53MEN1KMT2A | |
| SCHEMBL7334463 | 0.79 | LMNA (0.67) | LMNATP53NAMPTMEN1KMT2A | |
| SCHEMBL3279971 | 0.78 | MAPT (0.61) | MAPTLMNATP53THRBMEN1 | |
| SCHEMBL7333708 | 0.77 | MAPT (0.60) | MAPTLMNATP53THRBNR3C1 | |
| SCHEMBL7327269 | 0.77 | F2 (0.66) | MAPTLMNANAMPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |