Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 3/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276444 | 0.76 | HSD17B10 (0.53) | ALDH1A1HPGDKMT2AGLAKDM4E | |
| SCHEMBL4299906 | 0.75 | ALDH1A1 (0.70) | ALDH1A1HPGDKMT2AGLAGAA | |
| SCHEMBL28216929 | 0.75 | TOP2A (0.42) | ALDH1A1HPGDKMT2AGLAGAA | |
| SCHEMBL88355 | 0.75 | KMT2A (0.47) | ALDH1A1HPGDKMT2AGLAGAA | |
| SCHEMBL11690096 | 0.72 | ALDH1A1 (0.58) | ALDH1A1HPGDKMT2AGLAGAA | |
| SCHEMBL297515 | 0.72 | ALDH1A1 (0.58) | ALDH1A1HPGDKMT2AGLAGAA | |
| SCHEMBL29712310 | 0.72 | ALDH1A1 (0.58) | ALDH1A1HPGDKMT2AGLAGAA | |
| SCHEMBL30853545 | 0.72 | ALDH1A1 (0.58) | ALDH1A1HPGDKMT2AGLAGAA | |
| SCHEMBL4336758 | 0.72 | CA12 (0.45) | ALDH1A1HPGDKMT2AGLAGAA | |
| SCHEMBL30857473 | 0.72 | ALDH1A1 (0.64) | ALDH1A1HPGDKMT2AGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105669668-A | Pyridoindazole or benzopyridoindazole derivatives and synthesis method thereof | 上海大学 | 2016-06-15 | — | — | CN | disclosed |
| EP-0560231-B1 | Pyrazolo(3,4-a)acridine derivatives as analgesics | HOECHST MARION ROUSSEL INC (US) | 1998-06-03 | — | — | EP | disclosed |
| EP-0560231-A1 | Pyrazolo(3,4-a)acridine derivatives as analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-09-15 | — | — | EP | disclosed |