Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acridine SCHEMBL30991444 | 0.86 | ALDH1A1 (0.52) | KMT2AALDH1A1GLAHPGDGAA | |
| Acridine SCHEMBL30991443 | 0.86 | ALDH1A1 (0.52) | KMT2AALDH1A1GLAHPGDGAA | |
| SCHEMBL4336758 | 0.77 | CA12 (0.45) | KMT2AALDH1A1GLAHPGDGAA | |
| SCHEMBL4299906 | 0.77 | ALDH1A1 (0.70) | KMT2AALDH1A1GLAHPGDGAA | |
| SCHEMBL8547852 | 0.75 | ALDH1A1 (0.46) | KMT2AALDH1A1GLAHPGDGAA | |
| SCHEMBL634894 | 0.74 | PARP1 (0.53) | KMT2AALDH1A1GLAHPGDGAA | |
| SCHEMBL29712310 | 0.74 | ALDH1A1 (0.58) | KMT2AALDH1A1GLAHPGDGAA | |
| SCHEMBL30853545 | 0.74 | ALDH1A1 (0.58) | KMT2AALDH1A1GLAHPGDGAA | |
| SCHEMBL11690096 | 0.74 | ALDH1A1 (0.58) | KMT2AALDH1A1GLAHPGDGAA | |
| SCHEMBL297515 | 0.74 | ALDH1A1 (0.58) | KMT2AALDH1A1GLAHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 622 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120202201-A | Inhibitors of ubiquitin-specific protease 1 and uses thereof | 深圳晶泰科技有限公司 | 2025-06-24 | — | — | CN | claimed |
| WO-2024094170-A1 | INHIBITOR OF UBIQUITIN-SPECIFIC PROTEASE 1 AND USE THEREOF | 深圳晶泰科技有限公司 | 2024-05-10 | — | — | WO | claimed |
| CN-113956232-B | Quinoline-bisindole compound and preparation method and application thereof | 山东师范大学 | 2022-09-16 | — | — | CN | claimed |
| CN-113956232-A | Quinoline-bisindole compound and preparation method and application thereof | 山东师范大学 | 2022-01-21 | — | — | CN | claimed |
| CN-113774167-A | Saliva SARS-CoV-2 nucleic acid three-chain rapid detection kit | 陈超 | 2021-12-10 | — | — | CN | claimed |
| EP-2805945-B1 | Amide substituted indazoles as poly(ADP-ribose)polymerase (PARP) inhibitors | MSD ITALIA SRL (IT) | 2019-04-03 | — | — | EP | claimed |
| US-9837620-B2 | Benzopyridoindole derivative and organic electroluminescent element | HODOGAYA CHEMICAL CO., LTD. (JP) | 2017-12-05 | — | — | US | claimed |
| US-20160254458-A1 | BENZOPYRIDOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT | HODOGAYA CHEMICAL CO., LTD. (JP) | 2016-09-01 | — | — | US | claimed |
| EP-2646428-B1 | HETEROCYCLIC DERIVATIVES, PREPARATION PROCESSES AND MEDICAL USES THEREOF | SHANGHAI DE NOVO PHARMATECH CO LTD (CN) | 2016-06-01 | — | — | EP | claimed |
| EP-2646428-A1 | HETEROCYCLIC DERIVATES PREPARATION PROCESSES AND MEDICAL USES THEREOF | Shanghai De Novo Pharmatech Co Ltd. (CN) | 2013-10-09 | — | — | EP | claimed |
| US-20130224107-A1 | HETEROCYCLIC DERIVATES, PREPARATION PROCESSES AND MEDICAL USES THEREOF | SHANGHAI DE NOVO PHARMATECH CO LTD. (CN) | 2013-08-29 | — | — | US | claimed |
| WO-2012071684-A1 | HETEROCYCLIC DERIVATES，PREPARATION PROCESSES AND MEDICAL USES THEREOF | SHANGHAI DE NOVO PHARMATECH CO LTD. (CN) | 2012-06-07 | — | — | WO | claimed |
| US-20070054905-A1 | Use of indole-derived compounds for the preparation of a medicament that can be used to treat diseases related to the splicing process | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2007-03-08 | — | — | US | claimed |
| EP-1663219-A2 | USE OF INDOLE-DERIVED COMPOUNDS FOR THE PREPARATION OF A MEDICAMENT THAT CAN BE USED TO TREAT DISEASES RELATED TO THE SPLICING PROCESS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2006-06-07 | — | — | EP | claimed |
| WO-2005023255-A2 | USE OF INDOLE-DERIVED COMPOUNDS FOR THE PREPARATION OF A MEDICAMENT THAT CAN BE USED TO TREAT DISEASES RELATED TO THE SPLICING PROCESS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2005-03-17 | — | — | WO | claimed |
| US-12473549-B2 | Splicing-dependent transcriptional gene silencing or activation | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2025-11-18 | — | — | US | disclosed |
| CN-120202201-A | Inhibitors of ubiquitin-specific protease 1 and uses thereof | 深圳晶泰科技有限公司 | 2025-06-24 | — | — | CN | disclosed |
| EP-0882801-A1 | Method for selecting cDNA fragments | INSTITUT PASTEUR DE LILLE (FR) | 1998-12-09 | — | — | EP | disclosed |
| EP-0864002-A1 | METHODS AND COMPOSITIONS FOR DETECTION OF SPECIFIC NUCLEOTIDE SEQUENCES | Ramberg, Elliot R. (US) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997015691-A1 | METHODS AND COMPOSITIONS FOR DETECTION OF SPECIFIC NUCLEOTIDE SEQUENCES | RAMBERG ELLIOT R (US) | 1997-05-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160254458-A1 | BENZOPYRIDOINDOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT | SLCO2B1, SLCO4C1, LEF1 | KMT2A 1512/4885ALDH1A1 950/4885GLA 4369/4885 |
| US-20130224107-A1 | HETEROCYCLIC DERIVATES, PREPARATION PROCESSES AND MEDICAL USES THEREOF | PARP1, PARP3, PARP2 | KMT2A 1827/4885ALDH1A1 407/4885GLA 1036/4885 |
| US-20070054905-A1 | Use of indole-derived compounds for the preparation of a medicament that can be used to treat diseases related to the splicing process | RBM17, BRCA1, SMN1; SMN2 | KMT2A 4150/4885ALDH1A1 2690/4885GLA 3557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.