Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080841 | 0.90 | HTR6 (0.72) | HTR6KMT2ATSHRHTTPOLB | |
| SCHEMBL27903364 | 0.79 | HTR6 (0.57) | HTR6KMT2ATSHRHTTPOLB | |
| SCHEMBL29469862 | 0.79 | HTR6 (0.63) | HTR6KMT2ATSHRHTTPOLB | |
| SCHEMBL794103 | 0.79 | HTR6 (0.63) | HTR6KMT2ATSHRHTTPOLB | |
| SCHEMBL30014725 | 0.79 | HTR6 (0.57) | HTR6KMT2ATSHRHTTPOLB | |
| SCHEMBL4616548 | 0.79 | ALDH1A1 (0.58) | HTR6KMT2ATSHRHTTPOLB | |
| SCHEMBL1516456 | 0.79 | TSHR (0.58) | HTR6KMT2ATSHRHTTPOLB | |
| SCHEMBL31618370 | 0.79 | HTR6 (0.57) | HTR6KMT2ATSHRHTTPOLB | |
| SCHEMBL9793431 | 0.78 | HTR6 (0.62) | HTR6KMT2ATSHRHTTPOLB | |
| Potassium Ion SCHEMBL7638087 | 0.77 | HTR6 (0.55) | HTR6KMT2ATSHRHTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596917-B1 | BENZIMIDAZOLE ANTHELMINTICS | PFIZER LTD (GB) | 1998-10-28 | — | — | EP | claimed |