SCHEMBL8548256

SCHEMBL8548256

Oc1ccc(CCOc2ncnc3ccccc23)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.57
NPC1 O15118 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
TSHR P16473 1/20 0.57
LMNA P02545 4/20 0.57
POLB P06746 1/20 0.53
CYP1A2 P05177 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
RXFP1 Q9HBX9 2/20 0.49
ABCG2 Q9UNQ0 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
GAA P10253 1/20 0.44
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.41
HTT P42858 2/20 0.41
EGFR P00533 1/20 0.41
APP P05067 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8542382 0.93 RAB9A (0.56) RAB9ANPC1L3MBTL1TSHRLMNA
SCHEMBL8548739 0.88 RAB9A (0.69) RAB9ANPC1L3MBTL1TSHRLMNA
SCHEMBL8546894 0.87 LMNA (0.64) RAB9ANPC1L3MBTL1TSHRLMNA
SCHEMBL8542920 0.85 RAB9A (0.57) RAB9ANPC1L3MBTL1TSHRLMNA
SCHEMBL8544698 0.85 RAB9A (0.61) RAB9ANPC1L3MBTL1TSHRLMNA
SCHEMBL8544725 0.85 LMNA (0.74) RAB9ANPC1L3MBTL1TSHRLMNA
SCHEMBL8542022 0.85 RAB9A (0.59) RAB9ANPC1L3MBTL1TSHRLMNA
SCHEMBL9162456 0.85 RAB9A (0.57) RAB9ANPC1L3MBTL1TSHRLMNA
SCHEMBL8542357 0.85 RAB9A (0.58) RAB9ANPC1L3MBTL1TSHRLMNA
SCHEMBL3729705 0.85 LMNA (0.54) RAB9ANPC1L3MBTL1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0326329-B1 Quinazoline derivatives useful as insecticides. DOW AGROSCIENCES LLC (US) 1998-10-28 EP disclosed