Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 2/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | CCR3 | P51677 | 2/20 | 0.38 |
| ▸ | CCR2 | P41597 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8591795 | 1.00 | CARM1 (0.43) | CARM1PRMT6GRIN2BGRIN2DGRIN3B | |
| SCHEMBL8544988 | 0.93 | MEN1 (0.41) | CARM1PRMT6GRIN2BBCHECCR3 | |
| SCHEMBL8544991 | 0.93 | MEN1 (0.41) | CARM1PRMT6GRIN2BBCHECCR3 | |
| SCHEMBL8543130 | 0.93 | MEN1 (0.41) | CARM1PRMT6GRIN2BBCHECCR3 | |
| SCHEMBL8541668 | 0.91 | GRIN2B (0.51) | GRIN2BGRIN2DGRIN3BADRA1DADRA1A | |
| SCHEMBL8591796 | 0.88 | CARM1 (0.43) | CARM1PRMT6GRIN2BGRIN2DGRIN3B | |
| SCHEMBL8548411 | 0.88 | CARM1 (0.43) | CARM1PRMT6GRIN2BGRIN2DGRIN3B | |
| SCHEMBL8873521 | 0.84 | CARM1 (0.43) | CARM1PRMT6GRIN2BBCHEHTR2A | |
| SCHEMBL8542893 | 0.84 | CARM1 (0.43) | CARM1PRMT6GRIN2BBCHEHTR2A | |
| SCHEMBL8542815 | 0.82 | ALDH1A1 (0.42) | CARM1PRMT6HTR2ACCR3CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709384-B1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GMBH (DE) | 1998-12-23 | — | — | EP | disclosed |
| US-5698553-A | Benzylpiperidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-16 | — | — | US | disclosed |
| EP-0709384-A1 | Benzylpiperidine derivatives having high affinity for binding sites of aminoacid receptors | MERCK PATENT GmbH (DE) | 1996-05-01 | — | — | EP | disclosed |