Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 20/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.52 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8797719 | 0.81 | PTGS2 (0.63) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 | |
| SCHEMBL1812902 | 0.81 | PTGS2 (0.58) | PTGS2 | |
| SCHEMBL7452447 | 0.79 | PTGS2 (0.59) | PTGS2PTGS1KDM4EMT-CO1MT-CO2 | |
| SCHEMBL4214071 | 0.79 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL6724238 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL387063 | 0.79 | ENPP2 (0.61) | PTGS2 | |
| SCHEMBL386705 | 0.78 | ENPP2 (0.55) | PTGS2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL4938374 | 0.77 | SLC6A4 (0.58) | PTGS2PTGS1KDM4ECYP1A2CYP2C9 | |
| SCHEMBL27362321 | 0.77 | PTGS2 (0.54) | PTGS2 | |
| SCHEMBL13448493 | 0.77 | PTGS2 (0.72) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |