Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | TP53 | P04637 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 6/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL8549235 | 0.95 | MAPT (0.36) | MAPTTP53KDM4EMEN1CYP1A2 | |
| Malonic Acid SCHEMBL7147604 | 0.85 | KDM4E (0.44) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| Malonic Acid SCHEMBL8552650 | 0.85 | SMN1; SMN2 (0.34) | MAPTTP53KDM4ECYP1A2CYP3A4 | |
| Malonic Acid SCHEMBL7146355 | 0.80 | HTR1D (0.43) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 | |
| Malonic Acid SCHEMBL8550508 | 0.80 | SMN1; SMN2 (0.35) | MAPTKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8552137 | 0.76 | GNRHR (0.34) | MAPTTP53KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL8549069 | 0.75 | GNRHR (0.38) | MAPTTP53KDM4EMEN1CYP1A2 | |
| SCHEMBL28382188 | 0.60 | PARP1 (0.56) | TP53MTNR1AMTNR1BHTT | |
| SCHEMBL10669106 | 0.60 | NPSR1 (0.49) | MAPTTP53KDM4EMEN1CYP1A2 | |
| SCHEMBL7144826 | 0.59 | MAPT (0.45) | MAPTKDM4EMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015545-A1 | NEW SEROTONIN 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |