Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 6/20 | 0.33 |
| ▸ | TP53 | P04637 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549069 | 0.91 | GNRHR (0.38) | GNRHRMAPTTP53SMN1; SMN2KDM4E | |
| SCHEMBL7144826 | 0.81 | MAPT (0.45) | GNRHRMAPTSMN1; SMN2KDM4ELMNA | |
| SCHEMBL8553337 | 0.81 | GNRHR (0.34) | GNRHRSMN1; SMN2KDM4EKMT2ANPY5R | |
| SCHEMBL7145976 | 0.73 | GNRHR (0.48) | GNRHRMAPTSMN1; SMN2LMNAKMT2A | |
| SCHEMBL8551217 | 0.73 | GNRHR (0.37) | GNRHRSMN1; SMN2KDM4ELMNANPY5R | |
| SCHEMBL4001727 | 0.62 | KDM4E (0.47) | SMN1; SMN2KDM4E | |
| SCHEMBL6430952 | 0.61 | SIGMAR1 (0.49) | SMN1; SMN2KDM4E | |
| SCHEMBL8549636 | 0.61 | HTR1F (0.51) | MAPTSMN1; SMN2KDM4ELMNAKMT2A | |
| Hydrochloric Acid SCHEMBL8553027 | 0.59 | NPC1 (0.40) | MAPTSMN1; SMN2KDM4EKMT2AALDH1A1 | |
| SCHEMBL11922686 | 0.59 | SIGMAR1 (0.49) | SMN1; SMN2KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |